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This is an open access article distributed under the terms of the article, given that original files were not available for assessment in a number of instances and the integrity issues surrounding the preparation of Fig 2B, although the PLOS Biology Editors issue this Expression of concern: A chaperonin subunit with unique structures is essential for folding of a Specific Substrate. Splicing concerns were raised for several figures in this article, including panels of Figs 3A, 3B, 3C and 4B, and panels in this. The underlying data provided by the authors support the other results reported in the supporting information files.

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